A Single Important Dose of The HPV Vaccine Helps?

A new study conducted at hospitals across India found that a single dose of the human papillomavirus (HPV) vaccine can prevent cervical cancer, despite the Union government’s dismissal of reports of its inclusion in routine immunisation programmes.

HPV is a sexually transmitted infection that causes nearly all cases of cervical cancer.

The study included 2,135 women aged 10 and up, divided into groups who received one, two, or three doses of HPV vaccines between the ages of 10 and 18.

According to a study published in the journal Human Vaccines and Immunotherapeutics, 10 years after vaccination, a significant proportion of single-dose recipients still had antibody titers against HPV types 16 and 18. The proportion was slightly higher among 10–14-year-olds than those aged 15–18.

Early this year, media reports stated that the HPV vaccine would be included in the Indian government’s vaccine programme, aimed at 14-year-old girls. However, the Press Information Bureau has clarified that no such decision has been made yet. “The Union Health Ministry has yet to make a decision on the rollout of HPV vaccination in the country. It is closely monitoring the incidence of cervical cancer cases in the country and is in regular contact with states and various health departments about it,” the PIB stated.

According to the new study aimed to investigate the long-term antibody response to a single HPV vaccine dose.

“The study showed that a single-dose jab with a catch-up extended to age 20 will have a more significant impact on reducing the lifetime risk of cervical cancer and accelerating the elimination of the disease than administering two doses to pre-adolescent girls.”

Cervical cancer is the second most common type of cancer among Indian women, following breast cancer. Throughout the world, the HPV vaccine has been recognised as an important preventive measure. The World Health Organisation recommends that girls aged 9 to 14 be given one or two HPV doses. A recent study in Scotland discovered no cases of cervical cancer among women who received the full HPV vaccine.

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